Genetic and chromosomal abnormalities could be the cause, including Cystic Fibrosis, Klinefelter syndrome, and Y-chromosome deletions. Diseases, urological conditions, and medical procedures during a person’s life could also cause azoospermia: Vasectomy varicoceles are frequent causes, however, alternate etiologies such as being born with an undescended testicle (cryptorchidism), having the mumps at an older age, going through chemotherapy/radiation therapy, undergoing an operation for inguinal hernia, the infection should also be considered. Lastly, inadequate gonadotropin production is also a known cause of azoospermia. Usually, if irregular levels of testosterone and/or LH and FSH (too high/low) are measured, a problem in the production of sperm is presumably the cause of azoospermia.
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