Treatments depend on the underlying cause of the condition. Medications might work for retrograde ejaculation caused by nerve damage.
This type of damage can be caused by diabetes, multiple sclerosis, certain surgeries, and other conditions and treatments.
Drugs generally will not help if retrograde ejaculation is due to surgery that causes permanent physical changes in your anatomy. Examples include bladder neck surgery and transurethral resection of the prostate.
If a physician thinks drugs might be affecting the ability to ejaculate normally, he or she might recommend stopping taking them for a period of time. Drugs that can cause retrograde ejaculation include certain medications for depression and alpha-blockers — drugs used to treat high blood pressure and some prostate conditions.
Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including Imipramine (Tofranil), Midodrine, Chlorpheniramine (Chlor-Trimeton, others), brompheniramine (Veltane, others), Ephedrine (Akovaz, others), pseudoephedrine (Sudafed, others) and phenylephrine (Vazculep, others). These medications help keep the bladder neck muscle closed during ejaculation (With retrograde ejaculation, the bladder neck muscle doesn’t tighten properly.
As a result, sperm can enter the bladder instead of being ejected out of your body through the penis).
While they are often an effective treatment for retrograde ejaculation, medications can cause side effects or adverse reactions with other medications. Certain medications used to treat retrograde ejaculation can increase blood pressure and heart rate, which can be dangerous if a patient has high blood pressure or heart disease.
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